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Transthyretin (F87M/L110M) (1.0mg) Human, Recombinant

Transthyretin (F87M/L110M) (1.0mg) Human, Recombinant

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    Description

    Article no.: T-509-10

    Description




    Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. T
    F87M/L110M TTR is an engineered variant unable to form a stable tetramer.

    Amount

    1mg

    Format

    Lyophilized

    Molecular Weight

    13763.5 kDa

    Sequence

    GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKV
    EIDTKSYWKALGISPMHEHAEVVFTANDSGPRRYTIAAMLSPYSYSTTAVVTNPKE

    Purity

    95% by Chromatography and SDS-PAGE

    Counter Ion

    Ammonium Carbonate

    Solubility

    The lyophilized protein is readily soluble in PBS pH 7.4.

    Storage

    Store at -20°C upon arrival.

    Source

    Protein expressed in Escherichia coli.