AlexoTech Umeå

Publications with AlexoTech

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Transthyretin stabilizer therapy increases naturally-occurring antibodies in ATTR cardiomyopathy

Transthyretin stabilizer therapy increases naturally-occurring antibodies in ATTR cardiomyopathy

Shared Binding Properties Between a Therapeutic Antibody and Anti-Transthyretin Antibodies From Transthyretin Cardiac Amyloidosis Patients: Translational Implications for Future Clinical Trials

Shared Binding Properties Between a Therapeutic Antibody and Anti-Transthyretin Antibodies From Transthyretin Cardiac Amyloidosis Patients: Translational Implications for Future Clinical Trials

Silica-Embedded Proteins Enable Higher Yield and Atomic Ion Detection in Deep-UV Laser-Assisted Atom Probe Tomography

Silica-Embedded Proteins Enable Higher Yield and Atomic Ion Detection in Deep-UV Laser-Assisted Atom Probe Tomography

Tear fluid as a novel specimen for detection of alpha-synuclein seeding activity in Parkinson’s disease

Tear fluid as a novel specimen for detection of alpha-synuclein seeding activity in Parkinson’s disease

Amyloid beta pathology induces astrocytic pTDP-43 mislocalization and disrupts TDP-43-regulated cryptic exon transcripts

Amyloid beta pathology induces astrocytic pTDP-43 mislocalization and disrupts TDP-43-regulated cryptic exon transcripts

The Co(II) ion binds to the N-terminal region of amyloid-beta (Aβ) peptides and modulates Aβ aggregation

The Co(II) ion binds to the N-terminal region of amyloid-beta (Aβ) peptides and modulates Aβ aggregation

Alzheimer’s Aβ catalyzes Tau phase separation and aggregation via early nanocluster solubilization

Alzheimer’s Aβ catalyzes Tau phase separation and aggregation via early nanocluster solubilization

Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis

Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis

Single-molecule imaging of small aggregates of IAPP in type 2 diabetes serum with rationally-designed antibody-like scaffolds

Single-molecule imaging of small aggregates of IAPP in type 2 diabetes serum with rationally-designed antibody-like scaffolds

APOE isotype-dependent regulation of IgG and IgA levels against different IAPP epitopes

APOE isotype-dependent regulation of IgG and IgA levels against different IAPP epitopes

Binding of ApoE Isoforms to Aβ Peptides and Effects on Their Fibrillization

Binding of ApoE Isoforms to Aβ Peptides and Effects on Their Fibrillization

Disrupted glutathione homeostasis in the pathogenesis of TTR-V30M amyloidosis

Disrupted glutathione homeostasis in the pathogenesis of TTR-V30M amyloidosis

Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding

Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding

Cholesterol modulates vesicle clustering mediated by alpha-synuclein in a nonlinear fashion

Cholesterol modulates vesicle clustering mediated by alpha-synuclein in a nonlinear fashion

Binding of Hg(I) and Hg(II) Ions to Amyloid-Beta (Aβ) Peptide Variants Affect their Structure and Aggregation

Binding of Hg(I) and Hg(II) Ions to Amyloid-Beta (Aβ) Peptide Variants Affect their Structure and Aggregation

Biophysical analysis of angiotensin II and amyloid-β cross-interaction in aggregation and membrane disruption

Biophysical analysis of angiotensin II and amyloid-β cross-interaction in aggregation and membrane disruption

Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides

Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides

Correlative light and electron microscopy imaging of proteinaceous deposits in cell cultures and brain tissues

Correlative light and electron microscopy imaging of proteinaceous deposits in cell cultures and brain tissues

Recruitment of apolipoprotein E facilitates Herpes simplex virus 1 attachment and release

Recruitment of apolipoprotein E facilitates Herpes simplex virus 1 attachment and release

A Step-By-Step Protocol for Correlative Light and Electron Microscopy Imaging of Proteinaceous Deposits in Cultured Cells and Human Brain Tissues

A Step-By-Step Protocol for Correlative Light and Electron Microscopy Imaging of Proteinaceous Deposits in Cultured Cells and Human Brain Tissues

Transthyretin Levels and Instability in Alzheimer’s Disease: Correlations with AD Biomarkers in a Cohort Study

Transthyretin Levels and Instability in Alzheimer’s Disease: Correlations with AD Biomarkers in a Cohort Study

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.

Accumulation of alpha-synuclein pathology in the liver exhibits post-translational modifications associated with Parkinson’s disease

Accumulation of alpha-synuclein pathology in the liver exhibits post-translational modifications associated with Parkinson’s disease

Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers

Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers