Description
Article no.: TN-500-10
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Description |
Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10% of the population above 80 years of age with depositions mainly found in the heart. |
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Amount |
1mg |
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Format |
Lyophilized |
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Sequence |
GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKV |
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Purity |
95% by Chromatography and SDS-PAGE |
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Counter Ion |
Ammonium Carbonate |
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Solubility |
The lyophilized protein is readily soluble in PBS pH 7.4. |
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Storage |
Store at -20°C upon arrival. |
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Source |
Protein expressed in Escherichia coli using 15NH4-Cl as sole nitrogen source. |