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Apolipoprotein E3 (R136S) Christchurch (1.0 mg) Human, Recombinant

Apolipoprotein E3 (R136S) Christchurch (1.0 mg) Human, Recombinant

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    Description

    Article no.: AE-111-10

    Description



    Apolipoprotein E is part of the chylomicron and Intermediate-density lipoproteins essential for the normal
    processing of triglyceride-rich lipoproteins. ApoE is primarily produced by the liver and macrophages. In the
    central nervous system, ApoE is mainly produced by astrocytes and transports cholesterol to neurons via
    ApoE receptors. 

    Amount

    1mg

    Format

    Lyophilized

    Molecular Weight

    34298.77 Da

    Sequence







    MKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQ
    VTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDV
    CGRLVQYRGEVQAMLGQSTEELRVSLASHLRKLRKRLLRDADDLQKRLAVYQAGAR
    EGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGS
    RTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGL
    VEKVQAAVGTSAAPVPSDNH 

                       

    Purity

    >95% by Chromatography and SDS-PAGE

    QC Data



    SDS-PAGE (Coomassie)
    - Single band at ~14 kDa
    - >95% purity

    Mass Spectrometry
    - Observed mass: 34299.71 Da
    - Theoretical mass: 34298.77 Da

    Note: The images and data shown represent a typical QC batch and may not correspond to the current lot.

    Counter Ion

    Ammonium Carbonate

    Solubility

    ApoE is soluble in PBS. 

    Storage

    Store at -20°C upon arrival.

    Source

    Protein expressed in Escherichia coli.