Peptides and ProteinsApolipoprotein ERecombinant Variants of Human Apolipoprotein EApolipoprotein E3 (ApoE3) (1mg) 1-272 Human, Recombinant
Apolipoprotein E3 (ApoE3) (1mg) 1-272 Human, Recombinant

Apolipoprotein E3 (ApoE3) (1mg) 1-272 Human, Recombinant

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ApoE3 1-272, (methionine in -1 position), this variant lacks residue 273-299 known as the receptor-binding domain of ApoE.
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    Description

    Article no.: AE-110-10

    Description

    Apolipoprotein E is part of the chylomicron and Intermediate-density lipoproteins essential for the normal
    processing of triglyceride-rich lipoproteins. ApoE is primarily produced by the liver and macrophages. In
    the central nervous system, ApoE is mainly produced by astrocytes and transports cholesterol to neurons
    via ApoE receptors. 

    Amount

    1mg

    Format

    Lyophilized

    Molecular Weight

    31515.7 kDa
    Sequence 

    MKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSS
    QVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMED
    VCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKCLAVYQAGA
    REGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMG
    SRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDM
    Purity

    95% by Chromatography and SDS-PAGE

    Counter Ion

    Ammonium Carbonate

    Solubility

    ApoE is soluble in PBS. 

    Storage

    Store at -20°C upon arrival.

    Source

    Protein expressed in Escherichia coli.
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