Product Information

Immunogen	Synthetic peptide chosen from human Abeta (1-11) peptide. Amino acid sequence: DAEFRHDSGYE
Host	Rabbit
Clonality	Polyclonal
Purity	Affinity purified
Format	Lyophilized
Quantity	50 µg
Reconstitution	Add 50 ul sterile water to reconstitute to 1 mg/ml
Storage	Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Tested applications	Dot Blot (Dot), ELISA (ELISA)
Recommended Dilution	1 : 1000 (DB), 1 : 3000 (ELISA)
Expected \| apparent MW	4.5 kDa

Reactivity

Confirmed Reactivity	Human
Predicted Reactivity	Bovine, Chicken, Dog, Porcine, Rabbit
Not reactive in	No confirmed exceptions from predicted reactivity are currently known.

Application Examples

Application examples

Dot blot and Western analysis

Membrane: Nitrocellulose
Blocking buffer: 1% dry milk in PBS, 0.3% Tween 20
Antibody dilution : 1:1000
Secondary antibody: anti-rabbit (HRP)
Detection: Enhanced Chemoluminescence (pico) 300s

Additional Information

Additional information

The antibody display high affinity for monomers, oligomers and fibrils derived from Amyloid-Beta 1-40 and 1-42.

Related Products

Related products

Available antibodies for Alzheimer's disease

Background

Background

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein.

New Amyloid-Beta Antibodies

A­n­t­i­-­A­m­y­l­o­i­d­-­B­e­t­a 1-11, Rabbit, Polyclonal (AS19 4310)

A­n­t­i­-­A­m­y­l­o­i­d­-­B­e­t­a 18-30, Rabbit, Polyclonal (AS19 4308)

A­n­t­i­-­A­m­y­l­o­i­d­-­B­e­t­a 1-11, Rabbit, Polyclonal (AS19 4309)

Anti-Amyloid-Beta 1-11, Rabbit, Polyclonal (AS19 4310)

Anti-Amyloid-Beta 18-30, Rabbit, Polyclonal (AS19 4308)

Anti-Amyloid-Beta 1-11, Rabbit, Polyclonal (AS19 4309)