Description
Article no.: AS08 329
Product Information
|
Immunogen |
Synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: |
|
Host |
Chicken |
|
Clonality |
Polyclonal |
|
Purity |
Total IgY |
|
Format |
Liquid in PBS pH 8.0, 0.02% sodium azide |
|
Quantity |
100 µl |
|
Storage |
Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
|
Tested applications |
Dot Blot (Dot), ELISA (ELISA) |
|
Recommended Dilution |
1 : 1000 (DB), 1 : 500 (ELISA) |
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Expected | apparent MW |
4.5 kDa |
Reactivity
|
Confirmed Reactivity |
Human |
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Predicted Reactivity |
Bovine, Chicken, Dog, Porcine, Rabbit |
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Not reactive in |
No confirmed exceptions from predicted reactivity are currently known. |
Application Examples
|
Application examples |
Dot blot application example
 |
Additional Information
|
Additional information |
The antibody can detect Abeta(1-42), but does not react with Abeta(1-40), Abeta(1-41), Abeta(1-28) Abeta(1-20) or Abeta(1-17). |
Related Products
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Related products |
Background
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Background |
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein. |