Chimeric Proteins

Multiple Targeting of Surface Epitopes – The Next Generation of Antigens

Experiencing challenges with antibody generation? Structural and membrane-bound proteins often have regions that are either surface-exposed or hidden within the protein structure. Designing an effective antigen requires targeting these exposed domains with precision.

AlexoTech offers a structure-based design approach where multiple surface-exposed epitopes are carefully selected and fused into a novel chimeric protein. This next-generation design significantly increases the likelihood of producing highly effective polyclonal antibodies that recognize the native fold of the target protein.

This method is especially advantageous when working with membrane proteins — allowing selective targeting of loop regions on one specific side of the membrane for improved antigen performance.

Project Includes

• Structure-based antigen design
• Protein expression
• Purification of 5 mg of protein at >95% purity
• Ultra-high purification of 2 mg for immunization at >99% purity

Price: 2900 USD + DNA construct 1.49 USD/base

Contact us for more details about our chimeric protein design service.